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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50189188
(3-amino-N-((1S)-1-(2-(4-(3-(2,4-dichlorophenyl)pro...)
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Affinity Data
Ki: 13nM
Assay Description:
Activity at MC4R assessed as inhibition of alpha-MSH-stimulated cAMP production
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Melanocortin receptor 5
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50189188
(3-amino-N-((1S)-1-(2-(4-(3-(2,4-dichlorophenyl)pro...)
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Copy InChI
Affinity Data
Ki: 170nM
Assay Description:
Displacement of [125I]NDP-MSH from human MC5R expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50189188
(3-amino-N-((1S)-1-(2-(4-(3-(2,4-dichlorophenyl)pro...)
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Copy InChI
Affinity Data
Ki: 800nM
Assay Description:
Displacement of [125I]NDP-MSH from human MC3R expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50189188
(3-amino-N-((1S)-1-(2-(4-(3-(2,4-dichlorophenyl)pro...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.10E+3nM
Assay Description:
Acitivity at MC4R assessed as inhibition of alphaMSH-stimulated cAMP production
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI