Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50189188(3-amino-N-((1S)-1-(2-(4-(3-(2,4-dichlorophenyl)pro...)
Affinity DataKi:  13nMAssay Description:Activity at MC4R assessed as inhibition of alpha-MSH-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50189188(3-amino-N-((1S)-1-(2-(4-(3-(2,4-dichlorophenyl)pro...)
Affinity DataKi:  170nMAssay Description:Displacement of [125I]NDP-MSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50189188(3-amino-N-((1S)-1-(2-(4-(3-(2,4-dichlorophenyl)pro...)
Affinity DataKi:  800nMAssay Description:Displacement of [125I]NDP-MSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50189188(3-amino-N-((1S)-1-(2-(4-(3-(2,4-dichlorophenyl)pro...)
Affinity DataIC50:  1.10E+3nMAssay Description:Acitivity at MC4R assessed as inhibition of alphaMSH-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed