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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetE3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM299724((1R,3S,6S,7R)-7-(3-Chlorophenyl)-6-(4-chlorophenyl...)
Affinity DataIC50:  23.8nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM215426(US9296736, 414)
Affinity DataIC50:  23.8nMpH: 7.4 T: 2°CAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent