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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50025080
(1-(4-Chloro-2,3-dihydro-1H-indol-5-ylmethyl)-propy...)
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Affinity Data
IC50: 300nM
Assay Description:
Compound was tested in vitro for inhibition of Serotonin transporter uptake at serotonin uptake site
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Amine oxidase [flavin-containing] A/B
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50025080
(1-(4-Chloro-2,3-dihydro-1H-indol-5-ylmethyl)-propy...)
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Affinity Data
IC50: 630nM
Assay Description:
Compound was tested in vitro for inhibition of MAO by using [14C]5-HT as substrate in rat brain mitochondrial preparation
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Amine oxidase [flavin-containing] A/B
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50025080
(1-(4-Chloro-2,3-dihydro-1H-indol-5-ylmethyl)-propy...)
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Affinity Data
IC50: 1.45E+3nM
Assay Description:
Compound was tested in vitro for inhibition of MAO by using [14C]phenylethylamine as substrate in rat brain mitochondrial preparation
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Transporter
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50025080
(1-(4-Chloro-2,3-dihydro-1H-indol-5-ylmethyl)-propy...)
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Affinity Data
IC50: 1.60E+3nM
Assay Description:
In vitro inhibition of NE uptake at NE uptake site
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50025080
(1-(4-Chloro-2,3-dihydro-1H-indol-5-ylmethyl)-propy...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
In vivo inhibition of DA uptake at dopamine uptake site
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI