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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
C-X-C chemokine receptor type 2
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50200878
((R)-3-(2-(1-(furan-2-yl)propylamino)-3,4-dioxocycl...)
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Affinity Data
IC50: 3.80nM
Assay Description:
Displacement of [125I]hCXCL8 from human CXCR2 receptor expressed in BaF3 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
C-X-C chemokine receptor type 2
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50233563
(3-(2-(1-(furan-2-yl)propylamino)-3,4-dioxocyclobut...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5nM
Assay Description:
Inhibition of CXCR2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
C-X-C chemokine receptor type 1
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50200878
((R)-3-(2-(1-(furan-2-yl)propylamino)-3,4-dioxocycl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 26nM
Assay Description:
Displacement of [125I]hCXCL8 from human CXCR1 receptor expressed in BaF3 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
C-X-C chemokine receptor type 1
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50233563
(3-(2-(1-(furan-2-yl)propylamino)-3,4-dioxocyclobut...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 67nM
Assay Description:
Inhibition of CXCR1
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
C-X-C chemokine receptor type 1
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50200878
((R)-3-(2-(1-(furan-2-yl)propylamino)-3,4-dioxocycl...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 3.90nM
Assay Description:
Binding affinity to human CXCR1 assessed as dissociation constant incubated for 6 to 24 hrs by radioligand binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI
Target
C-X-C chemokine receptor type 2
(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by
ChEMBL
Ligand
BDBM50200878
((R)-3-(2-(1-(furan-2-yl)propylamino)-3,4-dioxocycl...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 0.0490nM
Assay Description:
Binding affinity to human CXCR2 assessed as dissociation constant incubated for 6 to 24 hrs by radioligand binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI