Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50253737
(CHEMBL453300 | N-((R)-3-(4-Fluorophenyl)-1-((S)-4-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 36nM
Assay Description:
Displacement of europium-labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50253737
(CHEMBL453300 | N-((R)-3-(4-Fluorophenyl)-1-((S)-4-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 428nM
Assay Description:
Displacement of europium-labeled NDP-alpha-MSH from human MC3R expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50253737
(CHEMBL453300 | N-((R)-3-(4-Fluorophenyl)-1-((S)-4-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.59E+3nM
Assay Description:
Agonist activity at human MC1R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50253737
(CHEMBL453300 | N-((R)-3-(4-Fluorophenyl)-1-((S)-4-...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.10E+3nM
Assay Description:
Agonist activity at human MC3R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50253737
(CHEMBL453300 | N-((R)-3-(4-Fluorophenyl)-1-((S)-4-...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 878nM
Assay Description:
Agonist activity at human MC1R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50253737
(CHEMBL453300 | N-((R)-3-(4-Fluorophenyl)-1-((S)-4-...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 37nM
Assay Description:
Agonist activity at human MC4R expressed in HEK293 cells assessed as effect on CRE-driven luminescence by luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI