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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Biovitrum
Ligand
BDBM22462
(2-Amino-1,3-thiazol-4(5H)-one, 5f | 2-{bicyclo[2.2...)
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Affinity Data
Ki: 73nM ΔG°: -40.3kJ/mole
pH: 7.2 T: 2°C
Assay Description:
The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
11-beta-hydroxysteroid dehydrogenase type 2
(Homo sapiens (Human))
Biovitrum
Ligand
BDBM22462
(2-Amino-1,3-thiazol-4(5H)-one, 5f | 2-{bicyclo[2.2...)
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Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
The assay was performed at room temperature in a 96-well microtiter plate containing substrate mixture [3H]cortisol/NAD+, inhibitors, and 11beta-HSD2...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI