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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
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kcal/mol
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Found
1
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Target
11-beta-hydroxysteroid dehydrogenase 1
(Homo sapiens (Human))
Biovitrum
Ligand
BDBM22454
(2-Amino-1,3-thiazol-4(5H)-one, 5b | 2-[(cyclohexyl...)
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Affinity Data
Ki: 64nM ΔG°: -40.6kJ/mole
pH: 7.2 T: 2°C
Assay Description:
The 11beta-HSD1 enzyme assay was carried out in the replica plates of the compounds in reaction buffer containing substrate mixture [3H]-cortisone/NA...
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