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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
27
hits in this display
Target
Acetylcholinesterase
(Homo sapiens (Human))
Universita Di Siena
Ligand
BDBM10597
((1S)-7-chloro-15-ethyl-10-azatetracyclo[11.3.1.0^{...)
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Affinity Data
Ki: 0.0260nM ΔG°: -60.4kJ/mole
pH: 8.0 T: 2°C
Assay Description:
The cholinesterase assays were performed using colorimetric method reported by E llman. Inhibition of enzyme activity was measured over a substrate c...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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In Depth
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Article
PubMed
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Target
Acetylcholinesterase
(Homo sapiens (Human))
Universita Di Siena
Ligand
BDBM10597
((1S)-7-chloro-15-ethyl-10-azatetracyclo[11.3.1.0^{...)
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Copy InChI
Affinity Data
Ki: 0.0260nM ΔG°: -60.4kJ/mole
pH: 7.0 T: 2°C
Assay Description:
Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
PDB
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In Depth
Details
Article
PubMed
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Target
Acetylcholinesterase
(Homo sapiens (Human))
Universita Di Siena
Ligand
BDBM50369748
(CHEMBL208599)
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Affinity Data
Ki: 0.0260nM
Assay Description:
Inhibitory activity against human AChE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
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Target
Acetylcholinesterase
(Tetronarce californica (Pacific electric ray) (Tor...)
Universit£
Curated by
ChEMBL
Ligand
BDBM50369748
(CHEMBL208599)
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Affinity Data
Ki: 0.130nM
Assay Description:
Inhibition of Torpedo californica AChE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
Universita Di Siena
Ligand
BDBM50369748
(CHEMBL208599)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.670nM
Assay Description:
Binding affinity to human AChE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinesterase
(Homo sapiens (Human))
Universita Di Siena
Ligand
BDBM10597
((1S)-7-chloro-15-ethyl-10-azatetracyclo[11.3.1.0^{...)
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Affinity Data
Ki: 120nM ΔG°: -39.5kJ/mole
pH: 8.0 T: 2°C
Assay Description:
The cholinesterase assays were performed using colorimetric method reported by E llman. Inhibition of enzyme activity was measured over a substrate c...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinesterase
(Homo sapiens (Human))
Universita Di Siena
Ligand
BDBM50369748
(CHEMBL208599)
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Affinity Data
Ki: 120nM
Assay Description:
Inhibitory activity against Equine Butyrylcholinesterase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Bos taurus (bovine))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50369748
(CHEMBL208599)
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Affinity Data
IC50: 0.230nM
Assay Description:
Compound was evaluated for the inhibition of acetylcholinesterase activity from bovine erythrocytes after 30 minutes of incubation
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Bos taurus (bovine))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50369748
(CHEMBL208599)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.230nM
Assay Description:
Compound was evaluated for the inhibition of acetylcholinesterase activity from bovine erythrocytes after 30 minutes of incubation
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
Universita Di Siena
Ligand
BDBM10597
((1S)-7-chloro-15-ethyl-10-azatetracyclo[11.3.1.0^{...)
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Copy InChI
Affinity Data
IC50: 0.320nM
Assay Description:
Inhibitory activity against human erythrocyte acetylcholinesterase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
Universita Di Siena
Ligand
BDBM50369748
(CHEMBL208599)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.75nM
Assay Description:
Inhibition of acetylcholinesterase isolated from Human erythrocytes.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
Universita Di Siena
Ligand
BDBM50369748
(CHEMBL208599)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.75nM
Assay Description:
Inhibition of acetylcholinesterase isolated from Human erythrocytes.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
Universita Di Siena
Ligand
BDBM50369748
(CHEMBL208599)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.10nM
Assay Description:
Inhibition of human recombinant AChE in erythrocytes by Ellman's assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Bos taurus (bovine))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM10597
((1S)-7-chloro-15-ethyl-10-azatetracyclo[11.3.1.0^{...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.30nM
Assay Description:
In vitro inhibitory activity against bovine acetylcholinesterase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Bos taurus (bovine))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50200343
((-)-(7S,11S)-huprine H7)
Copy SMILES
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Affinity Data
IC50: 1.30nM
Assay Description:
Inhibition of bovine erythrocyte AChE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Bos taurus (bovine))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50369748
(CHEMBL208599)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.77nM
Assay Description:
Compound was evaluated for the inhibition of acetylcholinesterase of bovine erythrocytes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Bos taurus (bovine))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50369748
(CHEMBL208599)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.77nM
Assay Description:
Compound was evaluated for the inhibition of acetylcholinesterase of bovine erythrocytes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Bos taurus (bovine))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM10597
((1S)-7-chloro-15-ethyl-10-azatetracyclo[11.3.1.0^{...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.77nM
Assay Description:
Inhibition of bovine erythrocyte AChE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Bos taurus (bovine))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50369748
(CHEMBL208599)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.34nM
Assay Description:
Compound was evaluated for the inhibition of acetylcholinesterase activity from bovine erythrocytes after 0 minutes of incubation
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Bos taurus (bovine))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50369748
(CHEMBL208599)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.34nM
Assay Description:
Compound was evaluated for the inhibition of acetylcholinesterase activity from bovine erythrocytes after 0 minutes of incubation
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinesterase
(Homo sapiens (Human))
Universita Di Siena
Ligand
BDBM50369748
(CHEMBL208599)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15.8nM
Assay Description:
Inhibition of butyrylcholinesterase (BChE) in human serum
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinesterase
(Homo sapiens (Human))
Universita Di Siena
Ligand
BDBM50369748
(CHEMBL208599)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15.8nM
Assay Description:
Inhibition of butyrylcholinesterase (BChE) in human serum
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
Universita Di Siena
Ligand
BDBM50369748
(CHEMBL208599)
Copy SMILES
Copy InChI
Affinity Data
IC50: 23.1nM
Assay Description:
Inhibition of acetylcholinesterase isolated from Human erythrocytes.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinesterase
(Homo sapiens (Human))
Universita Di Siena
Ligand
BDBM50369748
(CHEMBL208599)
Copy SMILES
Copy InChI
Affinity Data
IC50: 58.3nM
Assay Description:
Inhibition of butyrylcholinesterase (BChE) in human serum
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Bos taurus (bovine))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50369748
(CHEMBL208599)
Copy SMILES
Copy InChI
Affinity Data
IC50: 240nM
Assay Description:
Compound was evaluated for the inhibition of acetylcholinesterase activity from bovine erythrocytes after 0 minutes of incubation
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Bos taurus (bovine))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50369748
(CHEMBL208599)
Copy SMILES
Copy InChI
Affinity Data
IC50: 350nM
Assay Description:
Compound was evaluated for the inhibition of acetylcholinesterase activity from bovine erythrocytes after 30 minutes of incubation
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Bos taurus (bovine))
Universitat De Barcelona
Curated by
ChEMBL
Ligand
BDBM50369748
(CHEMBL208599)
Copy SMILES
Copy InChI
Affinity Data
IC50: 402nM
Assay Description:
Compound was evaluated for the inhibition of acetylcholinesterase of bovine erythrocytes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI