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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 60 hits in this display   

TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  0.100nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50281663(10-cyclopropylmethyl-1-ethyl-4-hydroxy-13-methyl-(...)
Affinity DataKi:  0.210nMAssay Description:Tested in vitro for binding affinity against Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails Article
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  0.300nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50430605(CHEMBL2338715 | Rel-Ethylketazocine)
Affinity DataKi:  0.390nMAssay Description:Displacement of [3H]-diprenorphine from human KOR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  0.400nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  0.570nMAssay Description:Binding affinity for the Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  0.620nMAssay Description:Binding affinity towards Opioid receptor kappa 1 in guinea pig brain membranes using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  0.620nMAssay Description:Binding affinity against opioid receptor kappa 1 using [3H]-U-69,593 as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  0.620nMAssay Description:Binding affinity to KOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  0.620nMAssay Description:Binding affinity towards Opioid receptor kappa 1 from guinea pig brain using [3H]U69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  0.620nMAssay Description:Displacement of [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  0.620nMAssay Description:Binding affinity towards Opioid receptor kappa 1 by displacing the radioligand [3H]U-69593 from guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  0.620nMAssay Description:Binding affinity was determined towards opioid receptor kappa 1 using [3H]U69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  0.620nMAssay Description:Displacement of [3H]U69,593 from KOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  0.620nMAssay Description:Displacement of [3H]U69593 form kappa opioid receptor in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity against opioid receptor mu 1 using [3H]-DAMGO as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  0.780nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranes after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity to MOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  0.780nMAssay Description:Displacement of [3H]DAMGO form mu opioid receptor in guinea pig brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity towards Opioid receptor mu 1 by displacing the radioligand [3H]DAMGO from guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  0.780nMAssay Description:Displacement of [3H]DAMGO from Opioid receptor mu 1 of guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity towards Opioid receptor mu 1 from guinea pig brain using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity towards Opioid receptor mu 1 in guinea pig brain membranes using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  0.780nMAssay Description:Binding affinity was determined towards opioid receptor mu1 using [3H]-DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50281663(10-cyclopropylmethyl-1-ethyl-4-hydroxy-13-methyl-(...)
Affinity DataKi:  1nMAssay Description:Tested in vitro for binding affinity against mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
Targetkappa-type opioid receptor isoform 1(Frog)
Biological Research Center Of Hungarian Academy Of Sciences

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  1.20nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity for the Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by PDSP Ki Database
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  1.93nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(GUINEA PIG)
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
In DepthDetails PubMed
Targetkappa-type opioid receptor isoform 1(Frog)
Biological Research Center Of Hungarian Academy Of Sciences

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  2.10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by PDSP Ki Database
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  2.12nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  2.30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by PDSP Ki Database
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  2.46nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  3.10nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity to DOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity against opioid receptor delta 1 using [3H]-naltrindole as radioligand in guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]naltrindole from Opioid receptor delta 1 of guinea pig brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity towards Opioid receptor delta 1 in guinea pig brain membranes using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity towards Opioid receptor delta 1 from guinea pig brain using [3H]naltrindole as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity towards Opioid receptor delta 1 by displacing the radioligand [3H]naltrindole from guinea pig brain membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOpioid receptor delta 1(Cavia porcellus)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]Naltrindole from DOR in guinea pig brain membranes after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity was determined towards Opioid receptor delta 1 using [3H]-Naltrindole as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  3.40nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
In DepthDetails ArticlePubMed
Targetkappa-type opioid receptor isoform 1(Frog)
Biological Research Center Of Hungarian Academy Of Sciences

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  23nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  28.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataKi:  101nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  188nMAssay Description:Binding affinity for kappa opioid receptor was evaluated by displacing [3H]- diprenorphineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by PDSP Ki Database
LigandPNGBDBM50045114(3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  690nMAssay Description:Binding affinity for mu opioid receptor was evaluated by displacing [3H]- diprenorphineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Kappa-type/Mu-type opioid receptor(Homo sapiens (Human))
Glaxo Group Research

Curated by ChEMBL
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataIC50:  5.90nMAssay Description:In vitro inhibitory activity against opioid receptor in Guinea pig ileumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataIC50:  8.40nMAssay Description:Ability to displace 50% of (+/-) ethylketocyclazocine (2.8) in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50281663(10-cyclopropylmethyl-1-ethyl-4-hydroxy-13-methyl-(...)
Affinity DataIC50:  29nMAssay Description:Binding affinity against opioid receptor kappa in guinea pig brain membrane using [3H]bremazocine as the radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataIC50:  47nMAssay Description:Ability to induce 50% of maximal effect in rabbit vas deferens expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Michigan

Curated by PDSP Ki Database
LigandPNGBDBM50430605(CHEMBL2338715 | Rel-Ethylketazocine)
Affinity DataEC50:  4.40nMAssay Description:Agonist activity at rat recombinant MOR expressed in rat C6 cells assessed as stimulation of [35S]GTPgammaS binding after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataEC50:  5.5nMAssay Description:Incorporation of [35S]- GTPgammaS into CHO membranes expressing human Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50430605(CHEMBL2338715 | Rel-Ethylketazocine)
Affinity DataEC50:  2.20nMAssay Description:Agonist activity at human KOR expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50000091((6S,11R)-3-Cyclopropylmethyl-6-ethyl-8-hydroxy-11-...)
Affinity DataEC50:  1.10nMAssay Description:Incorporation of [35S]GTP-gamma-S, into CHO membranes expressing human Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Sri International

Curated by PDSP Ki Database
LigandPNGBDBM50256687(CHEMBL4065923)
Affinity DataEC50:  2.20nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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