Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50017207(CHEMBL3287722 | US10099993, Compound 71)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of rat mGluR3 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017207(CHEMBL3287722 | US10099993, Compound 71)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017207(CHEMBL3287722 | US10099993, Compound 71)
Affinity DataEC50:  104nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50017207(CHEMBL3287722 | US10099993, Compound 71)
Affinity DataEC50:  104nMAssay Description:Positive allosteric modulation of rat mGluR2 receptor expressed in HEK293 cells assessed as potentiation of glutamate-induced thallium flux incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed