Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetNeprilysin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50190753(2-((1-((5-benzyl-1,3,4-thiadiazol-2-yl)carbamoyl)c...)Copy SMILESCopy InChI

Affinity DataIC50:  30nMAssay Description:Inhibition of dog NEPMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50190753(2-((1-((5-benzyl-1,3,4-thiadiazol-2-yl)carbamoyl)c...)Copy SMILESCopy InChI

Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of dog ACEMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI