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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
Genome polyprotein
(Hepatitis C virus)
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50152748
((S)-2-((S)-2-{(S)-2-Cyclohexyl-2-[(pyrazine-2-carb...)
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Affinity Data
Ki: 80nM
Assay Description:
Inhibition of HCV NS3 protease in the pNA based inhibition assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cathepsin B
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50152748
((S)-2-((S)-2-{(S)-2-Cyclohexyl-2-[(pyrazine-2-carb...)
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Affinity Data
Ki: 1.30E+4nM
Assay Description:
Binding affinity towards human cathepsin B
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Trypsin
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50152748
((S)-2-((S)-2-{(S)-2-Cyclohexyl-2-[(pyrazine-2-carb...)
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Affinity Data
Ki: >5.00E+4nM
Assay Description:
Binding affinity towards human trypsin
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Plasminogen
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50152748
((S)-2-((S)-2-{(S)-2-Cyclohexyl-2-[(pyrazine-2-carb...)
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Affinity Data
Ki: >5.00E+4nM
Assay Description:
Binding affinity towards human plasmin
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Chymotrypsinogen B
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50152748
((S)-2-((S)-2-{(S)-2-Cyclohexyl-2-[(pyrazine-2-carb...)
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Affinity Data
Ki: >5.00E+4nM
Assay Description:
Binding affinity towards human Chymotrypsinogen
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Prothrombin
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50152748
((S)-2-((S)-2-{(S)-2-Cyclohexyl-2-[(pyrazine-2-carb...)
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Copy InChI
Affinity Data
Ki: >5.00E+4nM
Assay Description:
Binding affinity towards human thrombin
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Procathepsin L
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50152748
((S)-2-((S)-2-{(S)-2-Cyclohexyl-2-[(pyrazine-2-carb...)
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Copy InChI
Affinity Data
Ki: 1.07E+5nM
Assay Description:
Binding affinity towards human cathepsin L
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI