Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Dartmouth College

US Patent

LigandBDBM50360304(CHEMBL516093 | US9149492, Beauveriolide I)Copy SMILESCopy InChI

Affinity DataIC50:  600nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Dartmouth College

US Patent

LigandBDBM50360304(CHEMBL516093 | US9149492, Beauveriolide I)Copy SMILESCopy InChI

Affinity DataIC50:  780nMAssay Description:Inhibition of ACAT1- mediated cholesteryl ester synthesis in macrophagesMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSterol O-acyltransferase 2(Homo sapiens (Human))
Dartmouth College

US Patent

LigandBDBM50360304(CHEMBL516093 | US9149492, Beauveriolide I)Copy SMILESCopy InChI

Affinity DataIC50:  2.00E+4nMAssay Description:Methods for assessing the selectively of ACAT1 inhibitors are known in the art and can be based upon any conventional assay including, but not limite...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI