Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetApelin receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50077998(CHEMBL3414600)
Affinity DataKi:  9.10nMAssay Description:Displacement of [125I]apelin-13[Glp65,Nle75,Tyr77] from YFP epitope-tagged human APJ receptor expressed in HEK293 cell membranes incubated for 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApelin receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50077998(CHEMBL3414600)
Affinity DataIC50:  11nMAssay Description:Displacement of [125I]apelin-13[Glp65,Nle75,Tyr77] from YFP epitope-tagged human APJ receptor expressed in HEK293 cell membranes incubated for 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApelin receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50077998(CHEMBL3414600)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as induction of Galphai1 subunit dissociation incubated for 5 mins by BRET ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApelin receptor(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50077998(CHEMBL3414600)
Affinity DataEC50:  3.10nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced intracellular cAMP production incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed