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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Melanocortin receptor 4
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50268795
(Ac-Nle-c[Asp-trans-4-guanidinyl-Pro-DPhe-Arg-Trp-L...)
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Affinity Data
IC50: 0.600nM
Assay Description:
Displacement of [125I][Nle4,Dphe7]-alpha-MSH from human MC4R expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Melanocortin receptor 3
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50268795
(Ac-Nle-c[Asp-trans-4-guanidinyl-Pro-DPhe-Arg-Trp-L...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1nM
Assay Description:
Displacement of [125I][Nle4,Dphe7]-alpha-MSH from human MC3R expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 5
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50268795
(Ac-Nle-c[Asp-trans-4-guanidinyl-Pro-DPhe-Arg-Trp-L...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.5nM
Assay Description:
Displacement of [125I][Nle4,Dphe7]-alpha-MSH from human MC5R expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50268795
(Ac-Nle-c[Asp-trans-4-guanidinyl-Pro-DPhe-Arg-Trp-L...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.70nM
Assay Description:
Agonist activity at human MC1R expressed in HEK293 cells assessed as stimulation of intracellular cAMP level
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50268795
(Ac-Nle-c[Asp-trans-4-guanidinyl-Pro-DPhe-Arg-Trp-L...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 3.50E+3nM
Assay Description:
Agonist activity at human MC4R expressed in HEK293 cells assessed as stimulation of intracellular cAMP level
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50268795
(Ac-Nle-c[Asp-trans-4-guanidinyl-Pro-DPhe-Arg-Trp-L...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 820nM
Assay Description:
Agonist activity at human MC1R expressed in HEK293 cells assessed as stimulation of intracellular cAMP level
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 3
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50268795
(Ac-Nle-c[Asp-trans-4-guanidinyl-Pro-DPhe-Arg-Trp-L...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 14nM
Assay Description:
Agonist activity at human MC3R expressed in HEK293 cells assessed as stimulation of intracellular cAMP level
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 5
(Homo sapiens (Human))
University Of Arizona
Curated by
ChEMBL
Ligand
BDBM50268795
(Ac-Nle-c[Asp-trans-4-guanidinyl-Pro-DPhe-Arg-Trp-L...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.60nM
Assay Description:
Agonist activity at human MC5R expressed in HEK293 cells assessed as stimulation of intracellular cAMP level
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI