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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072714(5-Butyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Affinity DataKi:  0.950nMAssay Description:Binding affinity was determined against hPR-A (human progesterone receptor) using progesterone radioligand in competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072714(5-Butyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Affinity DataKi:  813nMAssay Description:Displacement of Dexamethasone from human glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072714(5-Butyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Affinity DataKi:  2.05E+3nMAssay Description:Displacement of DHT from human androgen receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072714(5-Butyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Affinity DataEC50:  997nMAssay Description:Antagonist activity against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50072714(5-Butyl-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza...)
Affinity DataEC50:  11nMAssay Description:Binding affinity was determined against hPR-A (human progesterone receptor) using progesterone radioligand in competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed