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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50:  18nMAssay Description:Inhibition of Gelatinase B, matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50:  21nMAssay Description:Inhibition of Gelatinase A, matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50:  78nMAssay Description:Inhibition of collagenase-3, Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human neutrophil collagenase-I, Matrix metalloproteinase-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Stromelysin, matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099123(5-Hexyl-5-(4-phenoxy-phenyl)-pyrimidine-2,4,6-trio...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of matrilysin, Matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed