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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Department Of Chemistry And Applied Biosciences
Curated by
ChEMBL
Ligand
BDBM50317425
(10-Gingerol | CHEMBL549472)
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Affinity Data
Ki: 3.74E+3nM
Assay Description:
Displacement of [3H]8-OH-DPAT from 5HT1A receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counting
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Target
Cytochrome P450 2C8
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317425
(10-Gingerol | CHEMBL549472)
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Affinity Data
IC50: 2.00E+3nM
Assay Description:
Inhibition of CYP2C8 in human liver microsomes using amodiaquin as substrate preincubated for 10 mins followed by NADPH addition measured after 10 mi...
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Target
Cytochrome P450 2B6
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317425
(10-Gingerol | CHEMBL549472)
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Affinity Data
IC50: 4.30E+3nM
Assay Description:
Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate preincubated for 10 mins followed by NADPH addition measured after 20 min...
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Target Info
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KEGG
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317425
(10-Gingerol | CHEMBL549472)
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Affinity Data
IC50: 6.60E+3nM
Assay Description:
Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate preincubated for 10 mins followed by NADPH addition measured after...
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Target Info
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317425
(10-Gingerol | CHEMBL549472)
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Affinity Data
IC50: 7.10E+3nM
Assay Description:
Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate preincubated for 10 mins followed by NADPH addition measured after 10 ...
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Target Info
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317425
(10-Gingerol | CHEMBL549472)
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Affinity Data
IC50: 7.50E+3nM
Assay Description:
Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate preincubated for 10 mins followed by NADPH addition measured after 7 min...
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Target Info
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Target
Cytochrome P450 2C19
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317425
(10-Gingerol | CHEMBL549472)
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Affinity Data
IC50: 1.36E+4nM
Assay Description:
Inhibition of recombinant human CYP2C19 expressed in baculosomes using Vivid EOMCC substrate blue measured every 30 sec for 30 mins by fluorescence a...
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Target
Leukotriene A-4 hydrolase
(Homo sapiens (Human))
Mansoura University
Curated by
ChEMBL
Ligand
BDBM50210068
(CHEMBL3883497)
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Affinity Data
IC50: 1.52E+4nM
Assay Description:
Inhibition of recombinant C-terminal His-tagged human LTA4H epoxide hydrolase activity expressed in Escherichia coli assessed as reduction in LTB4 pr...
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Target Info
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Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317425
(10-Gingerol | CHEMBL549472)
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Affinity Data
IC50: 1.63E+4nM
Assay Description:
Binding affinity towards human melanocortin 4 receptor (hMC4R)
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Target Info
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317425
(10-Gingerol | CHEMBL549472)
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Affinity Data
IC50: 2.08E+4nM
Assay Description:
Inhibition of recombinant human CYP3A4 expressed in baculosomes using Vivid BOMCC substrate blue measured every 30 sec for 30 mins by fluorescence as...
More data for this Ligand-Target Pair
Target Info
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Target
Leukotriene A-4 hydrolase
(Homo sapiens (Human))
Mansoura University
Curated by
ChEMBL
Ligand
BDBM50210068
(CHEMBL3883497)
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Affinity Data
IC50: 2.16E+4nM
Assay Description:
Inhibition of recombinant C-terminal His-tagged human LTA4H aminopeptidase activity expressed in Escherichia coli using L-alanine-4-nitro-anilide hyd...
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317425
(10-Gingerol | CHEMBL549472)
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Affinity Data
IC50: 2.18E+4nM
Assay Description:
Inhibition of recombinant human CYP3A4 expressed in baculosomes using Vivid DBOMF substrate green measured every 30 sec for 30 mins by fluorescence a...
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Target Info
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Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317425
(10-Gingerol | CHEMBL549472)
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Affinity Data
IC50: 2.49E+4nM
Assay Description:
Inhibition of recombinant human CYP3A4 expressed in baculosomes using Vivid BOMR substrate red measured every 30 sec for 30 mins by fluorescence assa...
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317425
(10-Gingerol | CHEMBL549472)
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Affinity Data
IC50: 5.49E+4nM
Assay Description:
Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate preincubated for 10 mins followed by NADPH addition measured after...
More data for this Ligand-Target Pair
Target Info
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Target
Cytochrome P450 2A6
(Homo sapiens (Human))
Hanyang University
Curated by
ChEMBL
Ligand
BDBM50317425
(10-Gingerol | CHEMBL549472)
Copy SMILES
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Affinity Data
IC50: 9.83E+4nM
Assay Description:
Inhibition of CYP2A6 in human liver microsomes using Coumarin as substrate preincubated for 10 mins followed by NADPH addition measured after 15 mins
More data for this Ligand-Target Pair
Target Info
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Target
Aldo-keto reductase family 1 member B1
(Homo sapiens (Human))
Kyushu University
Curated by
ChEMBL
Ligand
BDBM50317425
(10-Gingerol | CHEMBL549472)
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Affinity Data
IC50: 1.26E+5nM
Assay Description:
Inhibition of protein kinase C epsilon expressed in Sf-9 cells
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