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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetAcid ceramidase(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50392472(CHEMBL408217)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of aCDaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50392472(CHEMBL408217)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of acid ceramidase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50392472(CHEMBL408217)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of acid ceramidase in human HaCaT cell lysatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcid ceramidase(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50392472(CHEMBL408217)
Affinity DataIC50:  2.77E+4nMAssay Description:Inhibition of ACDase in human MCF7 cell lysate using [9,10-3H] De-C16-Cer substrate after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral ceramidase(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50392472(CHEMBL408217)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of recombinant human nCDase expressed in Sf9 cells using fluorescently-labeled acyl-NBD-C12-ceramide as substrate after 2 hrs by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutral ceramidase(Homo sapiens (Human))
Humboldt Universit£T Zu Berlin

Curated by ChEMBL
LigandPNGBDBM50392472(CHEMBL408217)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of human recombinant neutral ceramidase using Acyl-NBD-C12-cer as substrate after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed