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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Plasminogen activator inhibitor 1/Tissue-type plasminogen activator
(Homo sapiens (Human))
University Of Michigan
US Patent
Ligand
BDBM264614
(US9718760, C158)
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Affinity Data
IC50: 1.44E+3nM
T: 2°C
Assay Description:
PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
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Target
Plasminogen activator inhibitor 1/Urokinase-type plasminogen activator
(Homo sapiens (Human))
University Of Michigan
US Patent
Ligand
BDBM264614
(US9718760, C158)
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Affinity Data
IC50: 2.60E+3nM
pH: 7.4 T: 2°C
Assay Description:
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Antithrombin-III/Prothrombin
(Homo sapiens (Human))
University Of Michigan
US Patent
Ligand
BDBM264614
(US9718760, C158)
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Affinity Data
IC50: 5.47E+5nM
T: 2°C
Assay Description:
PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI