Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetSterol O-acyltransferase 1(Rattus norvegicus)
TBA

Curated by ChEMBL

LigandBDBM50287511(1-Cyclohexyl-3-(2,6-diisopropyl-phenyl)-1-(2-dodec...)Copy SMILESCopy InChI

Affinity DataIC50:  31nMAssay Description:Liver Acyl coenzyme A:cholesterol acyltransferase inhibitory activity was determined in vitro using [1-14C]-oleolyl-CoA and microsomes isolated from ...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails Article
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TargetSterol O-acyltransferase 1(Mus musculus)
TBA

Curated by ChEMBL

LigandBDBM50287511(1-Cyclohexyl-3-(2,6-diisopropyl-phenyl)-1-(2-dodec...)Copy SMILESCopy InChI

Affinity DataIC50:  3.10E+3nMAssay Description:Compound was tested for its ability to penetrate the cell wall and inhibit macrophage ACAT in cell culture using murine IC-21 macrophages (MAI)More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatents

In DepthDetails Article
Copy BDB DOI