Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Ewha Womans University

LigandPNGBDBM232203((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  2.10E+3nMpH: 7.4 T: 2°CAssay Description:For the binding assay, aliquots of receptor membranes, 0.25 nM [3H]8-OH-DPAT (8-hydroxy-2-(di-N-propylamino)tetralin, 154.3 Ci/mM; New England Nuclea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Ewha Womans University

LigandPNGBDBM232203((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  2.10E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from recombinant human 5-HT1A receptor expressed in CHO-K1 cell membranes after 60 mins by microbeta counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Ewha Womans University

LigandPNGBDBM232203((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  4.50E+3nMpH: 7.4Assay Description:Frozen membranes from a stable CHO-K1 cell line expressing the human recombinant 5-HT2C receptor (PerkinElmer) were used. For the binding assay, [3H]...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Ewha Womans University

LigandPNGBDBM232203((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  4.50E+3nMAssay Description:Displacement of [3H]Mesulergine from recombinant human 5-HT2C receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232203((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  5.00E+3nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232203((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  5.60E+3nMAssay Description:Displacement of [3H]LSD from human 5-HT7 receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232203((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  5.60E+3nMpH: 7.4 T: 2°CAssay Description:For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232203((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  6.70E+3nMpH: 7.4 T: 2°CAssay Description:For receptor binding assays, human 5-HT6 and 5-HT7 serotonin receptors expressed in CHO-K1 cells (PerkinElmer) were used. For 5-HT6 receptor binding,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Northwest University

Curated by ChEMBL
LigandPNGBDBM232203((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  6.70E+3nMAssay Description:Displacement of [3H]Imipramine from human 5-HT transporter expressed in HEK-293 cell membranes after 30 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Ewha Womans University

LigandPNGBDBM232203((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  6.80E+3nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of frozen membrane from a CHO-K1 cell line expressing the human recombinant 5-HT2A receptor (PerkinElmer) an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Ewha Womans University

LigandPNGBDBM232203((E)-N-Decyl-3-(3,4,5-trimethoxyphenyl) acrylamide ...)
Affinity DataIC50:  6.80E+3nMAssay Description:Displacement of [3H]Ketanserin from recombinant human 5-HT2A receptor expressed in CHO-K1 cell membranes after 60 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed