Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075892(CHEMBL83753 | N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-y...)
Affinity DataIC50:  330nMAssay Description:Binding affinity towards Beta-2 adrenergic receptor in CHO cells expressing the cloned human receptor using 1251-iodocyanopindololMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075892(CHEMBL83753 | N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-y...)
Affinity DataIC50:  330nMAssay Description:Binding affinity towards human Beta-2 adrenergic receptor expressed in CHO cells, using [125I]-iodocyanopindololMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075892(CHEMBL83753 | N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-y...)
Affinity DataIC50:  5.50E+3nMAssay Description:Binding affinity towards human Beta-1 adrenergic receptor expressed in CHO cells, using 1251-iodocyanopindololMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075892(CHEMBL83753 | N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-y...)
Affinity DataIC50:  5.50E+3nMAssay Description:Binding affinity towards Beta-1 adrenergic receptor in CHO cells expressing the cloned human receptor using 1251-iodocyanopindololMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075892(CHEMBL83753 | N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-y...)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity of the compound towards Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075892(CHEMBL83753 | N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-y...)
Affinity DataEC50:  3.40nMAssay Description:In vitro effective concentration against beta-3 adrenergic receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075892(CHEMBL83753 | N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-y...)
Affinity DataEC50:  2.95E+8nMAssay Description:In vitro effective concentration against beta-3 adrenergic receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50075892(CHEMBL83753 | N-{4-[2-((R)-2-Hydroxy-2-pyridin-3-y...)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity towards Beta-3 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed