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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Sterol O-acyltransferase 1
(Rattus norvegicus)
Dupont Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50037630
(3-(2,4-Difluoro-phenyl)-1-heptyl-1-[5-(1H-imidazol...)
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Affinity Data
IC50: 2.85E+3nM
Assay Description:
In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in rat hepatic microsomes by using AIV assay.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
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Target
Sterol O-acyltransferase 1
(Rattus norvegicus)
Dupont Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50037630
(3-(2,4-Difluoro-phenyl)-1-heptyl-1-[5-(1H-imidazol...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.90E+3nM
Assay Description:
In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Sterol O-acyltransferase 1
(Mus musculus)
Dupont Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50037630
(3-(2,4-Difluoro-phenyl)-1-heptyl-1-[5-(1H-imidazol...)
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Copy InChI
Affinity Data
IC50: 5.50E+3nM
Assay Description:
Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell culture by using J774 assay.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Copy BDB DOI