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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Monocarboxylate transporter 1
(Rattus norvegicus (Rat))
Medical School Duluth
Curated by
ChEMBL
Ligand
BDBM50092016
(CHEMBL3582412 | US9296728, 6)
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Affinity Data
IC50: 880nM
Assay Description:
Inhibition of MCT1-mediated lactate transport in rat RBE4 cells incubated for 15 mins by [14C]-lactate uptake assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
PubMed
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Target
Monocarboxylate transporter 1
(Rattus norvegicus (Rat))
Medical School Duluth
Curated by
ChEMBL
Ligand
BDBM50092016
(CHEMBL3582412 | US9296728, 6)
Copy SMILES
Copy InChI
Affinity Data
IC50: 950nM
pH: 7.43 T: 2°C
Assay Description:
The entire lactate uptake studies for the inhibition of MCT1 were carried out on RBE4 (Rat Brain Endothelial 4) cells. The expression of MCT1 on thes...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI