Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 21 hits in this display
BDBM18356((2R,3R,4R,5S)-1-hexyl-2-(hydroxymethyl)piperidine-...)
BDBM18356((2R,3R,4R,5S)-1-hexyl-2-(hydroxymethyl)piperidine-...)
BDBM18356((2R,3R,4R,5S)-1-hexyl-2-(hydroxymethyl)piperidine-...)
IC50: 110nMAssay Description:Inhibition of recombinant GBA2 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
BDBM50335396(CHEMBL1651554 | N-Hexyl-L-ido-1-deoxynojirimycin)
IC50: 140nMAssay Description:Inhibition of recombinant GBA2 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
BDBM50156354(1-Hexyl-2-hydroxymethyl-piperidine-3,4,5-triol | C...)
BDBM50156354(1-Hexyl-2-hydroxymethyl-piperidine-3,4,5-triol | C...)
BDBM50156354(1-Hexyl-2-hydroxymethyl-piperidine-3,4,5-triol | C...)
BDBM18356((2R,3R,4R,5S)-1-hexyl-2-(hydroxymethyl)piperidine-...)
BDBM50156354(1-Hexyl-2-hydroxymethyl-piperidine-3,4,5-triol | C...)
BDBM18356((2R,3R,4R,5S)-1-hexyl-2-(hydroxymethyl)piperidine-...)
IC50: 4.00E+3nMpH: 4.5 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...More data for this Ligand-Target Pair
BDBM18356((2R,3R,4R,5S)-1-hexyl-2-(hydroxymethyl)piperidine-...)
BDBM18356((2R,3R,4R,5S)-1-hexyl-2-(hydroxymethyl)piperidine-...)
IC50: >2.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
BDBM50335396(CHEMBL1651554 | N-Hexyl-L-ido-1-deoxynojirimycin)
IC50: 4.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
BDBM18356((2R,3R,4R,5S)-1-hexyl-2-(hydroxymethyl)piperidine-...)
IC50: 8.00E+4nMAssay Description:Inhibition of recombinant GBA1 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
BDBM50156354(1-Hexyl-2-hydroxymethyl-piperidine-3,4,5-triol | C...)
BDBM50156354(1-Hexyl-2-hydroxymethyl-piperidine-3,4,5-triol | C...)
BDBM50335396(CHEMBL1651554 | N-Hexyl-L-ido-1-deoxynojirimycin)
BDBM50335396(CHEMBL1651554 | N-Hexyl-L-ido-1-deoxynojirimycin)
BDBM18356((2R,3R,4R,5S)-1-hexyl-2-(hydroxymethyl)piperidine-...)
BDBM50335396(CHEMBL1651554 | N-Hexyl-L-ido-1-deoxynojirimycin)
BDBM50335396(CHEMBL1651554 | N-Hexyl-L-ido-1-deoxynojirimycin)
IC50: >1.00E+6nMAssay Description:Inhibition of recombinant GBA1 preincuabated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair