Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAcetylcholinesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50038732(CHEMBL413549 | Hexyl-carbamic acid 9-ethyl-9-aza-t...)Copy SMILESCopy InChI

Affinity DataIC50:  125nMAssay Description:In vitro inhibitory activity against human acetylcholinesteraseMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAcetylcholinesterase(Mus musculus (mouse))
Pfizer

Curated by ChEMBL

LigandBDBM50038732(CHEMBL413549 | Hexyl-carbamic acid 9-ethyl-9-aza-t...)Copy SMILESCopy InChI

Affinity DataIC50:  156nMAssay Description:Inhibitory activity against acetylcholinesterase in mice at the dose of 1.8 mg/kg via intraperitoneal administrationMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI