Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL

LigandBDBM50431269(CHEMBL2333035 | US9428465, 7)Copy SMILESCopy InChI

Affinity DataIC50:  417nMAssay Description:Inhibition of rat recombinant acid ceramidase expressed in human HEK293 cells using N-lauroylceramide as substrate incubated for 30 mins prior to sub...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAcid ceramidase(Rattus norvegicus (Rat))
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL

LigandBDBM50431269(CHEMBL2333035 | US9428465, 7)Copy SMILESCopy InChI

Affinity DataIC50:  420nMpH: 4.5Assay Description:r-AC protein samples were pre-incubated with various concentrations of test compounds or vehicle control in 100 mM NaH2PO4/citrate buffer pH 4.5, 0.1...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI