Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universita Degli Studi Di Torino

Curated by ChEMBL

LigandBDBM50324371(4-Hexyloxy-3-phenylsulfonylfuroxan | CHEMBL1215644)Copy SMILESCopy InChI

Affinity DataEC50:  3.35E+3nMAssay Description:Inhibition of MDR1 expressed in MDCK cells assessed as calcein AM accumulation by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Universita Degli Studi Di Torino

Curated by ChEMBL

LigandBDBM50324371(4-Hexyloxy-3-phenylsulfonylfuroxan | CHEMBL1215644)Copy SMILESCopy InChI

Affinity DataEC50:  1.20E+4nMAssay Description:Induction of MRP1 expressed in MDCK cells assessed as calcein AM accumulation by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI