Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Muscarinic acetylcholine receptor M1
(RAT)
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50062593
(3-(4-Hexylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-az...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.60nM
Assay Description:
Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) radioligand in rat hippocampus membranes
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M1
(RAT)
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50062593
(3-(4-Hexylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-az...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 28nM
Assay Description:
Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-Pirenzepine (Pz) radioligand in rat hippocampus membranes.
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human))
Eli Lilly
Curated by
ChEMBL
Ligand
BDBM50062593
(3-(4-Hexylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-az...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 225nM
Assay Description:
Effective concentration required for stimulation of phosphoinositol (PI) hydrolysis in the A9 L cell line transfected with the Muscarinic acetylcholi...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI