Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent

LigandBDBM232445(US9346795, 264)Copy SMILESCopy InChI

Affinity DataIC50:  40nMT: 2°CAssay Description:The assays were performed in black flat-bottom 384-well plates. The final assay volume was 55 μl prepared from additions of Biotin-Bcl-xL (Bcl-x...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent

LigandBDBM232445(US9346795, 264)Copy SMILESCopy InChI

Affinity DataIC50:  110nMT: 2°CAssay Description:The assays were performed in black flat-bottom 384-well plates. The final assay volume was 50 μl prepared from additions of Gst-Bcl-2 (Bcl-2: GE...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails US Patent
Copy BDB DOI