Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBcl-2-like protein 1(Homo sapiens (Human))
Bristol-Myers Squibb Research

Curated by ChEMBL

LigandBDBM50384346(CHEMBL2031015)Copy SMILESCopy InChI

Affinity DataIC50:  54nMAssay Description:Inhibition of Bcl-XL using fluoresceinated 18-mer Bim as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Bristol-Myers Squibb Research

Curated by ChEMBL

LigandBDBM50384346(CHEMBL2031015)Copy SMILESCopy InChI

Affinity DataIC50:  400nMAssay Description:Inhibition in GST-tagged Bcl2 using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI