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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Bcl-2-like protein 1
(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Ligand
BDBM50384361
(CHEMBL2031031 | US9346795, 96)
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Affinity Data
IC50: 60nM
T: 2°C
Assay Description:
The assays were performed in black flat-bottom 384-well plates. The final assay volume was 55 μl prepared from additions of Biotin-Bcl-xL (Bcl-x...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Bcl-2-like protein 1
(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Ligand
BDBM50384361
(CHEMBL2031031 | US9346795, 96)
Copy SMILES
Copy InChI
Affinity Data
IC50: 62nM
Assay Description:
Inhibition of Bcl-XL using fluoresceinated 18-mer Bim as substrate after 60 mins by FRET analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Apoptosis regulator Bcl-2
(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by
ChEMBL
Ligand
BDBM50384361
(CHEMBL2031031 | US9346795, 96)
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Copy InChI
Affinity Data
IC50: 120nM
Assay Description:
Inhibition in GST-tagged Bcl2 using [FAM]-IWIAQELRRIGDEFNAYY-NH2 as substrate after 60 mins by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Apoptosis regulator Bcl-2
(Homo sapiens (Human))
Bristol-Myers Squibb Research
Curated by
ChEMBL
Ligand
BDBM50384361
(CHEMBL2031031 | US9346795, 96)
Copy SMILES
Copy InChI
Affinity Data
IC50: 120nM
T: 2°C
Assay Description:
The assays were performed in black flat-bottom 384-well plates. The final assay volume was 50 μl prepared from additions of Gst-Bcl-2 (Bcl-2: GE...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI