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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
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kcal/mol
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Found
1
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Target
Polyunsaturated fatty acid lipoxygenase ALOX15
(Oryctolagus cuniculus (rabbit))
Bristol-Myers Squibb
Ligand
BDBM22253
(2,4,5-tri-substituted imidazole, 21a | 4-butyl-N-{...)
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Affinity Data
IC50: 14nM
Assay Description:
The inhibitory activity of the compounds against purified 15-LO enzyme was determined using a standard colorimetric assay in which the lipid hydroper...
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