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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Ciba-Geigy
Curated by
ChEMBL
Ligand
BDBM50042503
(CHEMBL331931 | N-hydroxy-N-[(6-phenoxy-2H-chromen-...)
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Affinity Data
IC50: 65nM
Assay Description:
Inhibitory concentration against human platelet 5-lipoxygenase in human whole blood
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Ciba-Geigy
Curated by
ChEMBL
Ligand
BDBM50042503
(CHEMBL331931 | N-hydroxy-N-[(6-phenoxy-2H-chromen-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 69nM
Assay Description:
In vitro inhibitory activity against 5-lipoxygenase by reduction of LTB4 formed in guinea pig polymorphonuclear leukocytes (PMNs).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI