Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
UDP-N-acetylmuramoylalanine--D-glutamate ligase
(Escherichia coli (strain K12))
Lek Pharmaceuticals
Ligand
BDBM26444
((2R)-2-[(6-butoxynaphthalene-2-)sulfonamido]pentan...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.80E+5nM
pH: 8.6 T: 2°C
Assay Description:
The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
UDP-N-acetylmuramoylalanine--D-glutamate ligase
(Escherichia coli (strain K12))
Lek Pharmaceuticals
Ligand
BDBM26444
((2R)-2-[(6-butoxynaphthalene-2-)sulfonamido]pentan...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.80E+5nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
UDP-N-acetylmuramoylalanine--D-glutamate ligase
(Escherichia coli (strain K12))
Lek Pharmaceuticals
Ligand
BDBM26444
((2R)-2-[(6-butoxynaphthalene-2-)sulfonamido]pentan...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.10E+5nM
Assay Description:
Binding affinity to 6x His-tagged and 15N/13C-labeled Escherichia coli MurD ligase measured at NMR signal 4 by 1H/13C-HSQC 2D NMR spectroscopy
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI
Target
UDP-N-acetylmuramoylalanine--D-glutamate ligase
(Escherichia coli (strain K12))
Lek Pharmaceuticals
Ligand
BDBM26444
((2R)-2-[(6-butoxynaphthalene-2-)sulfonamido]pentan...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.20E+5nM
Assay Description:
Binding affinity to 6x His-tagged and 15N/13C-labeled Escherichia coli MurD ligase measured at NMR signal 123 by 1H/13C-HSQC 2D NMR spectroscopy
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
MMDB
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
MMDB
PDB
3D Structure (crystal)
Copy BDB DOI