Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL

LigandBDBM50083800(2-(Butane-1-sulfonylamino)-3-({1-[3-(pyridin-2-yla...)Copy SMILESCopy InChI

Affinity DataIC50:  360nMAssay Description:Inhbitory activity against beta3-transfected 293 cells using alpha-V beta-3 antagonism assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL

LigandBDBM50083800(2-(Butane-1-sulfonylamino)-3-({1-[3-(pyridin-2-yla...)Copy SMILESCopy InChI

Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of aggregation of human gel-purified platelets (GPIIbIIIa GPP)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI