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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Type-2 angiotensin II receptor
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50030732
(CHEMBL323506 | N-{3-[3-Butyl-4-(3-fluoro-2'(tert-b...)
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Affinity Data
IC50: 0.170nM
Assay Description:
Inhibitory concentration of the compound against AT1 receptor from rat adrenal tissues.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Type-2 angiotensin II receptor
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50030732
(CHEMBL323506 | N-{3-[3-Butyl-4-(3-fluoro-2'(tert-b...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.240nM
Assay Description:
In vitro ability of the compound to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT2 receptor from rat midbrain
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Type-2 angiotensin II receptor
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50030732
(CHEMBL323506 | N-{3-[3-Butyl-4-(3-fluoro-2'(tert-b...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.240nM
Assay Description:
In vitro inhibitory activity against Angiotensin II receptor, type 2 in rat midbrain membrane preparations.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Type-1 angiotensin II receptor A/B
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50030732
(CHEMBL323506 | N-{3-[3-Butyl-4-(3-fluoro-2'(tert-b...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.700nM
Assay Description:
Inhibitory concentration against AT1 receptor from rat adrenal tissues.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Type-2 angiotensin II receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50030732
(CHEMBL323506 | N-{3-[3-Butyl-4-(3-fluoro-2'(tert-b...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.820nM
Assay Description:
Inhibitory concentration of the compound against cloned human AT1 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Type-1 angiotensin II receptor
(RABBIT)
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50030732
(CHEMBL323506 | N-{3-[3-Butyl-4-(3-fluoro-2'(tert-b...)
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Copy InChI
Affinity Data
IC50: 0.840nM
Assay Description:
In vitro inhibitory activity against Angiotensin II receptor, type 1 in rabbit aorta membrane preparations.
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Type-1 angiotensin II receptor
(RABBIT)
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50030732
(CHEMBL323506 | N-{3-[3-Butyl-4-(3-fluoro-2'(tert-b...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.840nM
Assay Description:
In vitro ability of the compound to inhibit the binding of radioligand 125I[Sar1,IIe8]AII to AT1 receptor from rabbit aorta
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Type-2 angiotensin II receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50030732
(CHEMBL323506 | N-{3-[3-Butyl-4-(3-fluoro-2'(tert-b...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 12nM
Assay Description:
In vitro inhibitory concentration of the compound against AT2 receptor from human adrenal tissues.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Type-1 angiotensin II receptor
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50030732
(CHEMBL323506 | N-{3-[3-Butyl-4-(3-fluoro-2'(tert-b...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 14nM
Assay Description:
In vitro inhibitory concentration of the compound against AT1 receptor from human adrenal tissues.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
Copy BDB DOI