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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Dipeptidase 1
(GUINEA PIG)
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50042555
(5-Butyl-2-phenyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
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Affinity Data
Ki: 5.90E+5nM
Assay Description:
In vitro apparent inhibition constant of porcine renal Dehydropeptidase-1.
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Type-1 angiotensin II receptor
(RABBIT)
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50042555
(5-Butyl-2-phenyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
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Affinity Data
IC50: 2.90nM
Assay Description:
Evaluation of Angiotensin II antagonistic activity by displacement of [125I]-Sar Ile-AII at the rabbit aorta Angiotensin II receptor, type 1
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Beta-lactamase
(Pseudomonas aeruginosa)
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50042555
(5-Butyl-2-phenyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
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Affinity Data
IC50: >2.00E+5nM
Assay Description:
Inhibition of metallo-beta-lactamase (MBL) from Pseudomonas aeruginosa mediated by the plasmid-borne IMP-1 enzyme.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Metallo-beta-lactamase type 2
(Bacteroides fragilis)
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50042555
(5-Butyl-2-phenyl-4-[2'-(1H-tetrazol-5-yl)-biphenyl...)
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Affinity Data
IC50: 2.00E+5nM
Assay Description:
Inhibition of metallo-beta-lactamase (MBL) from Bacteroides fragilis.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI