Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50328382(CHEMBL1258263 | ethyl 6-(3-butyl-1,2,4-oxadiazol-5...)
Affinity DataIC50:  69nMAssay Description:Inhibition of DGAT1 in human Caco2 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50328382(CHEMBL1258263 | ethyl 6-(3-butyl-1,2,4-oxadiazol-5...)
Affinity DataIC50:  73nMAssay Description:Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50328382(CHEMBL1258263 | ethyl 6-(3-butyl-1,2,4-oxadiazol-5...)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of human full-length flag-tagged ACAT1 expressed in baculovirus infected insect cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed