Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL

LigandBDBM50012275(CHEMBL3260000)Copy SMILESCopy InChI

Affinity DataIC50:  680nMAssay Description:Antagonist activity at human LXR-beta expressed in HEK293 cells assessed as inhibition of T0901317-induced effect after 16 hrs by luciferase reporter...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL

LigandBDBM50012275(CHEMBL3260000)Copy SMILESCopy InChI

Affinity DataIC50:  690nMAssay Description:Inverse agonist activity at human ROR-gamma1 expressed in HEK293 cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL

LigandBDBM50012275(CHEMBL3260000)Copy SMILESCopy InChI

Affinity DataIC50: >3.00E+3nMAssay Description:Antagonist activity at human LXR-alpha expressed in HEK293 cells assessed as inhibition of T0901317-induced effect after 16 hrs by luciferase reporte...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNuclear receptor ROR-beta(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL

LigandBDBM50012275(CHEMBL3260000)Copy SMILESCopy InChI

Affinity DataIC50:  4.90E+3nMAssay Description:Inverse agonist activity at human ROR-beta expressed in HEK293 cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetNuclear receptor ROR-alpha(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL

LigandBDBM50012275(CHEMBL3260000)Copy SMILESCopy InChI

Affinity DataIC50:  5.60E+3nMAssay Description:Inverse agonist activity at human ROR-alpha1 expressed in HEK293 cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI