Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 8 hits in this display
BDBM239075(US9416103, JWH-073-M4)
BDBM239075(US9416103, JWH-073-M4)
BDBM239075(US9416103, JWH-073-M4)
BDBM239075(US9416103, JWH-073-M4)
Ki: 78.3nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
BDBM239075(US9416103, JWH-073-M4)
BDBM239075(US9416103, JWH-073-M4)
Ki: 251nM ΔG°: -37.7kJ/moleT: 2°CAssay Description:Competition receptor binding was performed as previously described [Shoemaker et al., J. Pharmacol. Exp. Ther., 314:868-75]. Briefly, 50 μg of mou...More data for this Ligand-Target Pair
BDBM239075(US9416103, JWH-073-M4)
IC50: 225nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
BDBM239075(US9416103, JWH-073-M4)
IC50: 225nMAssay Description:Agonist activity at CB1 receptor in mouse Neuro2a cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 mins by liq...More data for this Ligand-Target Pair