Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetCannabinoid receptor 1(Mus musculus (Mouse))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM239075(US9416103, JWH-073-M4)
Affinity DataKi:  24nMAssay Description:Agonist activity at CB1 receptor in mouse Neuro2a cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 mins by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM239075(US9416103, JWH-073-M4)
Affinity DataKi:  24.2nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM239075(US9416103, JWH-073-M4)
Affinity DataKi:  78nMAssay Description:Agonist activity at human CB2 receptor transfected in CHO cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 2(Homo sapiens (Human))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM239075(US9416103, JWH-073-M4)
Affinity DataKi:  78.3nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM239075(US9416103, JWH-073-M4)
Affinity DataKi:  122nM ΔG°:  -39.5kJ/moleT: 2°CAssay Description:Competition receptor binding was performed as previously described [Shoemaker et al., J. Pharmacol. Exp. Ther., 314:868-75]. Briefly, 50 μg of mou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCannabinoid receptor 2(Homo sapiens (Human))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM239075(US9416103, JWH-073-M4)
Affinity DataKi:  251nM ΔG°:  -37.7kJ/moleT: 2°CAssay Description:Competition receptor binding was performed as previously described [Shoemaker et al., J. Pharmacol. Exp. Ther., 314:868-75]. Briefly, 50 μg of mou...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBioDB n*138 SEQ ID NO: 2(Artificial Organism)
University Of Arkansas

US Patent
LigandPNGBDBM239075(US9416103, JWH-073-M4)
Affinity DataIC50:  225nMAssay Description:A functional assay screen for the inhibition of adenylate cyclase (AC) activity was chosen as the subsequent assay. This screen would allow us to gai...More data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails US Patent
TargetCannabinoid receptor 1(Mus musculus (Mouse))
The University Of Kansas

Curated by ChEMBL
LigandPNGBDBM239075(US9416103, JWH-073-M4)
Affinity DataIC50:  225nMAssay Description:Agonist activity at CB1 receptor in mouse Neuro2a cells assessed as inhibition of forskolin-stimulated adenylyl cyclase activity after 15 mins by liq...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed