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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Organix
Curated by
ChEMBL
Ligand
BDBM50171262
(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
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Affinity Data
Ki: 4.40nM
Assay Description:
Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human))
Organix
Curated by
ChEMBL
Ligand
BDBM50171262
(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
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Affinity Data
Ki: 5.80nM
Assay Description:
Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]-LSD as radioligand with the compound (10 uM) dissolved in DMSO
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Organix
Curated by
ChEMBL
Ligand
BDBM50171262
(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 14nM
Assay Description:
Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Rattus norvegicus (Rat))
Organix
Curated by
ChEMBL
Ligand
BDBM50171262
(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
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Copy InChI
Affinity Data
Ki: 15.7nM
Assay Description:
Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand with the compound (10 uM) dissolved in DMSO
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Organix
Curated by
ChEMBL
Ligand
BDBM50171262
(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 200nM
Assay Description:
Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Organix
Curated by
ChEMBL
Ligand
BDBM50171262
(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 310nM
Assay Description:
Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Organix
Curated by
ChEMBL
Ligand
BDBM50171262
(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 595nM
Assay Description:
Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2C receptor determi...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Organix
Curated by
ChEMBL
Ligand
BDBM50171262
(1-Butyl-3-(2-dimethylamino-ethyl)-1H-indol-4-ol | ...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 32nM
Assay Description:
Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2A receptor determi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI