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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Bcl-2-related protein A1
(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by
ChEMBL
Ligand
BDBM50313354
(6-((cyclopropylmethyl)(propyl)amino)-N-(6-methyl-1...)
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Affinity Data
IC50: 1.40E+3nM
Assay Description:
Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by time resolved-FRET assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bcl-2-related protein A1
(Homo sapiens (Human))
Human Biomolecular Research Institute
Curated by
ChEMBL
Ligand
BDBM50313354
(6-((cyclopropylmethyl)(propyl)amino)-N-(6-methyl-1...)
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Copy InChI
Affinity Data
IC50: 2.60E+3nM
Assay Description:
Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sphingosine 1-phosphate receptor 3
(Homo sapiens (Human))
Merck Serono
US Patent
Ligand
BDBM50313354
(6-((cyclopropylmethyl)(propyl)amino)-N-(6-methyl-1...)
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Affinity Data
EC50: >2.00E+4nM
pH: 7.4 T: 2°C
Assay Description:
Measurements of 35S-GTPgammaS Binding: Membranes (1 to 10 µg protein) prepared as described above, were incubated in 96-well Scintiplates (PerkinElm...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Sphingosine 1-phosphate receptor 1
(Homo sapiens (Human))
Merck Serono
US Patent
Ligand
BDBM50313354
(6-((cyclopropylmethyl)(propyl)amino)-N-(6-methyl-1...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 12nM
pH: 7.4 T: 2°C
Assay Description:
Measurements of 35S-GTPgammaS Binding: Membranes (1 to 10 µg protein) prepared as described above, were incubated in 96-well Scintiplates (PerkinElm...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Sphingosine 1-phosphate receptor 1
(Homo sapiens (Human))
Merck Serono
US Patent
Ligand
BDBM50313354
(6-((cyclopropylmethyl)(propyl)amino)-N-(6-methyl-1...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 12nM
Assay Description:
Agonist activity at S1P1 receptor expressed in CHO cells after 60 mins by [35S]-GTPgammaS binding assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI