Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50210717(CHEMBL397275 | N1-((2S,3R)-4-(3-ethylbenzylamino)-...)Copy SMILESCopy InChI

Affinity DataIC50:  2nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50210717(CHEMBL397275 | N1-((2S,3R)-4-(3-ethylbenzylamino)-...)Copy SMILESCopy InChI

Affinity DataIC50:  150nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI