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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50294645(CHEMBL539976 | N1-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50:  10nMAssay Description:Binding affinity to BACE assessed as displacement of [3H]BMS-599240More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50294645(CHEMBL539976 | N1-((2S,3R)-1-(3,5-difluorophenyl)-...)
Affinity DataIC50: >333nMAssay Description:Inhibition of BACE1 in human HEK293 cells overexpressing APP with Swedish mutation assessed as inhibition of amyloidbeta 40 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed