Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL

LigandBDBM50276551(CHEMBL448678 | N-{[2S,3(R,S)]-2-[4-(1-Benzylpiperi...)Copy SMILESCopy InChI

Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of BACE1 in HEK293 cells transfected with human betaAPP695 mutant assessed as inhibition of amyloid beta (1 to 40) production after 24 hrs...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAcetylcholinesterase(Rattus norvegicus (rat))
Chinese Academy Of Sciences

Curated by ChEMBL

LigandBDBM50276551(CHEMBL448678 | N-{[2S,3(R,S)]-2-[4-(1-Benzylpiperi...)Copy SMILESCopy InChI

Affinity DataIC50:  1.68E+3nMAssay Description:Inhibition of AChE in rat cortex preincubated for 20 mins by Ellman methodMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI