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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
5-hydroxytryptamine receptor 1A
(Mus musculus (Mouse))
University Of G£Teborg
Curated by
ChEMBL
Ligand
BDBM50034366
(CHEMBL28437 | Trifluoro-methanesulfonic acid 7-dip...)
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Affinity Data
Ki: 0.800nM
Assay Description:
In vitro binding affinity towards 5-hydroxytryptamine 1A receptor by using [3H]-8-OH-DPAT as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50030001
(CHEMBL89014 | Trifluoro-methanesulfonic acid (R)-7...)
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Affinity Data
Ki: 3.80nM
Assay Description:
Inhibition of [3H]- 8-OH-DPAT binding to 5-HT1A-receptor from rat cerebral cortex membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50030001
(CHEMBL89014 | Trifluoro-methanesulfonic acid (R)-7...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.80nM
Assay Description:
Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50030003
(CHEMBL88994 | Trifluoro-methanesulfonic acid (S)-7...)
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Affinity Data
Ki: 9.5nM
Assay Description:
Inhibition of [3H]- 8-OH-DPAT binding to 5-HT1A-receptor from rat cerebral cortex membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50030003
(CHEMBL88994 | Trifluoro-methanesulfonic acid (S)-7...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.5nM
Assay Description:
Binding affinity of 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligand.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50034366
(CHEMBL28437 | Trifluoro-methanesulfonic acid 7-dip...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 9.60nM
Assay Description:
Binding affinity against 5-hydroxytryptamine 1A receptor in homogenated rat brain tissue, using by [3H]8-OH-DPAT as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
University Of G£Teborg
Curated by
ChEMBL
Ligand
BDBM50034366
(CHEMBL28437 | Trifluoro-methanesulfonic acid 7-dip...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 12nM
Assay Description:
In vitro binding affinity towards 5-hydroxytryptamine 1D receptor alpha by using [3H]5-HT as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
University Of G£Teborg
Curated by
ChEMBL
Ligand
BDBM50034366
(CHEMBL28437 | Trifluoro-methanesulfonic acid 7-dip...)
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Copy InChI
Affinity Data
Ki: 62nM
Assay Description:
In vitro binding affinity towards Dopamine receptor D2 by using [3H]U-86170 as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
University Of G£Teborg
Curated by
ChEMBL
Ligand
BDBM50034366
(CHEMBL28437 | Trifluoro-methanesulfonic acid 7-dip...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 127nM
Assay Description:
In vitro binding affinity towards 5-hydroxytryptamine 1D receptor alpha by using [3H]-5-HT as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(3) dopamine receptor
(Homo sapiens (Human))
University Of G£Teborg
Curated by
ChEMBL
Ligand
BDBM50034366
(CHEMBL28437 | Trifluoro-methanesulfonic acid 7-dip...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 273nM
Assay Description:
In vitro binding affinity towards Dopamine receptor D3 by using [3H]spiperone as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Homo sapiens (Human))
University Of G£Teborg
Curated by
ChEMBL
Ligand
BDBM50034366
(CHEMBL28437 | Trifluoro-methanesulfonic acid 7-dip...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >413nM
Assay Description:
In vitro binding affinity towards Dopamine receptor D2 by using [3H]spiperone as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Medicinaregatan
Curated by
ChEMBL
Ligand
BDBM50034366
(CHEMBL28437 | Trifluoro-methanesulfonic acid 7-dip...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 670nM
Assay Description:
Binding affinity against dopamine receptor D2 in rat brain tissue using [3H]spiperone
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI