Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))TBA

LigandBDBM50212622(CHEMBL57187)Copy SMILESCopy InChI

Affinity DataIC50:  100nMAssay Description:The compound was evaluated for its ability to displace [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor in cellular brain membranesMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

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Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))TBA

LigandBDBM50212622(CHEMBL57187)Copy SMILESCopy InChI

Affinity DataIC50:  340nMAssay Description:The compound was evaluated for its ability to displace [3H]5-HT from 5-hydroxytryptamine 1B receptor in cellular brain membranesMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails
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TargetSerotonin 2 (5-HT2) receptor(Homo sapiens (Human))TBA

LigandBDBM50212622(CHEMBL57187)Copy SMILESCopy InChI

Affinity DataIC50:  1.80E+4nMAssay Description:The compound was evaluated for its ability to displace [3H]ketanserin from 5-hydroxytryptamine 2 receptor in cellular brain membranesMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails
Copy BDB DOI