Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Hoechst-Roussel Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50048587
((3-Methyl-indol-1-yl)-propyl-pyridin-4-yl-amine | ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.30E+3nM
Assay Description:
Inhibitory activity against norepinephrine (NE) uptake in rat whole brain synaptosome preparation
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor
(RAT)
Hoechst-Roussel Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50048587
((3-Methyl-indol-1-yl)-propyl-pyridin-4-yl-amine | ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.50E+3nM
Assay Description:
Inhibitory activity against [3H]clonidine binding to Alpha-2 adrenergic receptor in rat cortex
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5
(RAT)
Hoechst-Roussel Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50048587
((3-Methyl-indol-1-yl)-propyl-pyridin-4-yl-amine | ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.50E+3nM
Assay Description:
Inhibition of [3H]quinuclidinyl benzilate (QNB) binding from rat forebrain membranes in the presence of Zn
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5
(RAT)
Hoechst-Roussel Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50048587
((3-Methyl-indol-1-yl)-propyl-pyridin-4-yl-amine | ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.90E+4nM
Assay Description:
Inhibition of [3H]quinuclidinyl benzilate (QNB) binding from rat forebrain membranes in the absence of Zn
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Rattus norvegicus (rat))
Hoechst-Roussel Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50048587
((3-Methyl-indol-1-yl)-propyl-pyridin-4-yl-amine | ...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.90E+4nM
Assay Description:
Inhibitory activity against acetylcholinesterase in rat striatal preparation
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI